5-substituted aminopyrazino[2′,1′:2,3]imidazo[4,5-C][2,7]naphthyridine compounds as CK2 inhibitors
5-substituted aminopyrazino[2′,1′:2,3]imidazo[4,5-C][2,7]naphthyridine compounds as CK2 inhibitors
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US 11,945,821 B1
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الصحة - Health
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2024
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مكتب البراءات الأمريكي - US Patent Office
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Haroun; Michelyne (Al-Ahsa, SA), Tratrat; Christophe (Al-Ahsa, SA)
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Novel 5-substituted aminopyrazino[2′,1′:2,3]imidazo[4,5-c][2,7]naphthyridine compounds, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The 5-substituted aminopyrazino[2′,1′:2,3]imidazo[4,5-c][2,7]naphthyridine compounds, identified as CK2 inhibitors, are useful as anticancer and/or antitumor agents, and as agents for treating other kinase-associated conditions including inflammation, pain, and certain immunological disorders, and other types of diseases such as diabetes, viral infection, neurodegenerative diseases.