عـرض براءة الإختـراع

Selective hypoxia inducible factor prolyl-hydroxylase inhibitors

• رقــم البراءة

  US 12,060,359 B1

• المجـال العلمى

  الصحة - Health

• سنة الإصدار

  2024

• مكتـب التسجيـل

  مكتب البراءات الأمريكي - US Patent Office

• أسماء المخترعين

  Shaaban; Saad (Sohag, EG), Al-Hajji; Ali Khalid (Al-Ahsa, SA), Al-Faiyz; Yasair (Al-Ahsa, SA), Negm; Amr (Sohag, EG)

• نبذة عن البـراءة

  Synthesis and characterization of organoselenium-based triazolo pyrimidines and their use in treating hypoxia and inhibiting prolyl-hydroxylase domain (PHD) activity. The organoselenium-based triazolo pyrimidines have the formula: ##STR00001## wherein R is selected from the group consisting of —SeCH.sub.3, —SePhenyl, —CH.sub.2SeCH.sub.3, and —CH.sub.2SePhenyl.