عـرض براءة الإختـراع

Adenosine receptor activity of methyl/ethyl 3-(substituted benzoyl)-6,8-dimethylindolizine-2-substituted-1-carboxylates

• رقــم البراءة

  US 11,974,991 B1

• المجـال العلمى

  الصحة - Health

• سنة الإصدار

  2024

• مكتـب التسجيـل

  مكتب البراءات الأمريكي - US Patent Office

• أسماء المخترعين

  Venugopala; Katharigatta N. (Al-Ahsa, SA), Michela; Buccioni (Camerino, IT), Marucci; Gabriella (Cmaerino, IT), Deb; Pran Kishore (Ranchi, IN), Morsy; Mohamed A. (Al-Ahsa, SA), Aldhubiab; Bandar (Al-Ahsa, SA), Attimarad; Mahesh (Al-Ahsa, SA), Nair; Anroop B. (Al-Ahsa, SA), Sreeharsha; Nagaraja (Al-Ahsa, SA), Chandrashekharappa; Sandeep (Lucknow, IN), Shashikanth; Sheena (Mysore, IN)

• نبذة عن البـراءة

  Adenosine receptor active compounds including 1,2,3,6,8-pentasubstituted indolizines and methods of using the same for inhibiting adenosine receptor activity are provided. These methods can be used to treat one or more pathological conditions of the central and peripheral nervous systems, such as but not limited to allergies, inflammation, glaucoma, brain ischemia, renal fibrosis, cancer, rheumatoid arthritis, psoriasis fatty liver diseases, stroke, pain, and any combination thereof.