Fusion peptide inhibitors of human coronavirus 229E
Fusion peptide inhibitors of human coronavirus 229E
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US 12,084,478 B1
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الصحة - Health
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2024
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مكتب البراءات الأمريكي - US Patent Office
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Kandeel; Mahmoud (Al-Ahsa, SA)
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Fusion peptide inhibitors of human coronavirus 229E are provided. The fusion peptide inhibitors of HCOV-229E include peptide #121 TABLE-US-00001 (SEQ ID NO: 2: HVLGDISGINASVVQIQKEIDRLNEVAKNLHESL IYLQE), and peptide #125 (SEQ ID NO: 3: HRLRQIRGIRARVVQIQKEIWRLNEVAKL LNESLIYLQE). The fusion peptide inhibitors of HCoV-229E may be administered to a subject in need thereof to inhibit or prevent HCOV-229E cellular entry or infection with HCoV-229E. The fusion peptide inhibitors of HCoV-229E may also be used in HCoV-229E inhibition assays.