7-Imino-5-(1H-indol-3-yl)-1,3-substituted-7,8-dihdropyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione as anti-inflammatory agents

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7-Imino-5-(1H-indol-3-yl)-1,3-substituted-7,8-dihdropyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione as anti-inflammatory agents

  • US 12,145,936 B1

  • الصحة - Health

  • 2024

  • مكتب البراءات الأمريكي - US Patent Office

  • Venugopala; Katharigatta N. (Al-Ahsa, SA), Kamat; Vinuta (Bangalore, IN), Venugopala; Rashmi (Durban, ZA), Kumar; Amit (Bangalore, IN), Poojary; Boja (Mangalagangothri, IN)

  • 7-Imino-5-(1H-indol-3-yl)-1,3-substituted-7,8-dihydropyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione derivatives, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The present compounds, identified as COX-2 inhibitors, are useful as anti-inflammatory agents.