Pyrazino[1′,2′:1,5]pyrazolo[4,3-b][1,6]naphthyridines compounds as CK2 inhibitors
Pyrazino[1′,2′:1,5]pyrazolo[4,3-b][1,6]naphthyridines compounds as CK2 inhibitors
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US 12,129,259B1
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الصحة - Health
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2024
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مكتب البراءات الأمريكي - US Patent Office
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Haroun; Michelyne (Al-Ahsa, SA), Tratrat; Christophe (Al-Ahsa, SA)
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Novel pyrazino[1′,2′:1,5]pyrazolo[4,3-b][1,6]naphthyridine, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The pyrazino[1′,2′:1,5]pyrazolo[4,3-b][1,6]naphthyridine compounds, identified as CK2 inhibitors, are useful as anticancer and/or antitumor agents, and as agents for treating other kinase-associated conditions including inflammation, pain, and certain immunological disorders, and other types of diseases such as diabetes, viral infection, neurodegenerative diseases.