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Method of making silver nanoparticles capped with Caralluma sinaica extract and treatment method using the same

  • US 12,201,650 B1

  • الصحة - Health

  • 2025

  • مكتب البراءات الأمريكي - US Patent Office

  • Ali; Enas Mohamed (Al Hasa, SA), Abdallah; Basem Mohamed (Al Hasa, SA)

  • In order to inhibit the growth of fungi, such as Cryptococcus neoformans, silver nanoparticles are synthesized and capped with an extract of Caralluma sinaica. The silver nanoparticles capped with the extract of Caralluma sinaica are made by adding the extract of Caralluma sinaica to an aqueous silver nitrate solution to reduce the silver nitrate and form a suspension of silver nanoparticles capped with the extract of Caralluma sinaica. The silver nanoparticles capped with the extract of Caralluma sinaica are removed from the suspension by centrifugation or the like. The silver nanoparticles capped with Caralluma sinaica extract exhibit strong antifungal activity. To treat a Cryptococcus neoformans infection, an effective dose of the silver nanoparticles capped with Caralluma sinaica extract may be administered to a patient in need thereof.