US 11,730,759B1
الصحة - Health
2023
مكتب البراءات الأمريكي - US Patent Office
Hany Mohamed Abd El-Lateef Ahmed, Al-Ahsa (SA); Mai Mostafa Khalaf Ali, Al-Ahsa (SA); Ahmed Mohammed Abu-Dief Mohammed, Al-Ahsa (SA); Mohammed Sherif Saddik Ibrahim, Al-Ahsa (SA); Ali Khames Abd El-Twab Morsy, Al-Ahsa (SA)
A composition for treating ulcerative colitis can include zinc oxide nanoparticles and sulfasalazine adsorbed onto a surface of the zinc oxide nanoparticles. The composition can be administered to a patient to treat ulcerative colitis or symptoms associated with ulcerative colitis. The composition can be administered at about 100 mg/kg of zinc oxide nanoparticles and up to about 12.2 mg/kg of sulfasalazine. These compositions exhibit synergistic effects in treating ulcerative colitis.