عـرض براءة الإختـراع

METHOD FOR PREVENTING MYOCARDIAL INFARCTION USING EUCALYPTOL

• رقــم البراءة

  US 11,602,519 Bl

• المجـال العلمى

  الصحة - Health

• سنة الإصدار

  2023

• مكتـب التسجيـل

  مكتب البراءات الأمريكي - US Patent Office

• أسماء المخترعين

  Maged Elsayed Mohamed, Al-Ahsa (SA); Bander Essa Aldhubiab, Al-Ahsa (SA); Nancy Safwat Abdeldaium Younis, Al-Ahsa (SA)

• نبذة عن البـراءة

  A method of treating or preventing myocardial infarction can include administering a therapeutically effective amount of eucalyptol (1,8-cineole) to a patient in need thereof. Eucalyptol can be a cardio-protective agent against myocar­ dial infarction by decreasing inflammatory mediators and attenuating apoptosis of myocardial cells. Eucalyptol can inhibit the Toll-Like Receptors (TLRs) cascade, particularly via the TLR4/MyD88/NF-KB pathway, to prevent or lessen myocardial infarction-accompanied inflammation and apop­ tosis. Eucalyptol has a high therapeutic index, minor toxic­ ity, and is well tolerated by the body.