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Method of making gold nanoparticles capped with Caralluma sinaica extract and treatment method using the same

  • US 12,076,339 B1

  • الصحة - Health

  • 2024

  • مكتب البراءات الأمريكي - US Patent Office

  • Ali; Enas Mohamed (Al Hasa, SA), Abdallah; Basem Mohamed (Al Hasa, SA)

  • In order to inhibit the growth of bacteria, such as methicillin-resistant S. aureus (MRSA), gold nanoparticles are synthesized and capped with an extract of Caralluma sinaica. The gold nanoparticles capped with the extract of Caralluma sinaica are made by adding the extract of Caralluma sinaica to an aqueous HAuCl.sub.4 solution to reduce the HAuCl.sub.4 and form a suspension of gold nanoparticles capped with the extract of Caralluma sinaica. An unreacted portion of the extract of Caralluma sinaica is removed from the suspension by centrifugation or the like, and the gold nanoparticles capped with the extract of Caralluma sinaica are then removed from the suspension by further centrifugation or the like. The gold nanoparticles capped with Caralluma sinaica extract exhibit strong antibacterial activity. To treat a MRSA infection, an effective dose of the gold nanoparticles capped with Caralluma sinaica extract may be administered to a patient in need thereof.