عـرض براءة الإختـراع

EXPERIMENTAL MODEL USING PAZOPANIB-INDUCED CARDIOTOXICITY

• رقــم البراءة

  US 11,903,944B1

• المجـال العلمى

  الصحة - Health

• سنة الإصدار

  2024

• مكتـب التسجيـل

  مكتب البراءات الأمريكي - US Patent Office

• أسماء المخترعين

  Nancy SafwatYounis, Al-Ahsa(SA); Maged Elsayed Mohamed, Al-Ahsa (SA)

• نبذة عن البـراءة

  An experimental model using pazopanib-induced cardiotoxicity is provided. The experimental model using pazopanib-induced cardiotoxicity includes administering an effective dosing regimen of pazopanib to induce cardiotoxicity in a subject. The induced cardiotoxicity may include hypertension, arrhythmia, or cardiac toxicity. The dosing regimen may include administering a single dose or administering one or more daily doses of pazopanib. The dosing regimen may continue for a period of time between at least 10 and at least 30 days. The dose of pazopanib may be between 25 and 350 mg/kg.