US 11,866,412 B1
الصحة - Health
2024
مكتب البراءات الأمريكي - US Patent Office
Christophe Tratrat, Al-Ahsa (SA); Michelyne Haroun, Al-Ahsa (SA)
Novel acridin-9-one derivative compounds having broad spectrum antibacterial activity, a method of making said compounds, methods of using said compounds, and a phar- maceutical composition comprising said compound(s) are provided. The acridin-9-one compounds have antimicrobial activity against various susceptible and resistant gram-posi- tive and gram-negative bacteria as well as drug resistant bacteria. They act as DNA gyrase and topoisomerase IV inhibitors and are satisfiable as a drug for infectious treat- ment.