VIRUS-LIKE PARTICLE (VLP)-BASED VACCINE AGAINST CVB4

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VIRUS-LIKE PARTICLE (VLP)-BASED VACCINE AGAINST CVB4

  • US 11,826,418B1

  • الصحة - Health

  • 2023

  • مكتب البراءات الأمريكي - US Patent Office

  • Jawhar Gharbi, Al-Ahsa (SA); Ikbel Hadj Hassine, Monastir (TN); Mohammed A. Almalki, Al-Ahsa (SA); Ameera Alyami, Al-Ahsa (SA); Manel Ben M’Hadheb, Monastir (TN).

  • The virus-like particle (VLP)-based vaccine against CVB4 infection includes a virus-like particle (VLP) derived from VP1 of Coxsackievirus B4 (CVB4). The vaccine is devoid of virus RNA. The virus-like particles may be in nanoparticle form and coated with a polymer coating. The polymeric coating may be albumin, e.g., bovine serum albumin (BSA).