FUSION PEPTIDE INHIBITORS OF HUMAN CORONAVIRUS 229E

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FUSION PEPTIDE INHIBITORS OF HUMAN CORONAVIRUS 229E

  • US 11,866,461B1

  • الصحة - Health

  • 2024

  • مكتب البراءات الأمريكي - US Patent Office

  • Mahmoud Kandeel, Al-Ahsa(SA)

  • Fusion peptide inhibitors of human coronavirus 229E are provided. The fusion peptide inhibitors of HCoV-229E include peptide #121 (SEQ ID NO: 2: HVLGDISGINASVVQIQKEIDRLNEVAKNLHESLIYLQE), and peptide #125 (SEQ ID NO: 3: HRLRQIRGIRARVVQIQKEIWRLNEVAKLLNESLIYLQE). The fusion peptide inhibitors of HCoV-229E may be administered to a subject in need thereof to inhibit or prevent HCoV-229E cellular entry or infection with HCoV-229E. The fusion peptide inhibitors of HCoV-229E may also be used in HCoV-229E inhibition assays.