Non-Specific Immune Responses Elicited By Phagocytes On The Dermatophyte: Trichophyton verrucosum

(Ali Fadl and Dr. Molar. And. T. Maken)

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Abstract

Trichophyton verrucosum is a zoophilic dermatophyte that causes ringworm in man and animals worldwide. Phagocytosis was demonstrated to be an effectual defence mechanism against few dermatophytes. Yet, the effect of this mechanism on T. verrucosum has not been established. The objective of the study was to determine the cytotoxic effects of polymorphic neutrophils (PMN) and mononuclear leukocytes (MNL) collected from normal, experimentally infected or vaccinated guinea pigs on T. verrucosum spores and germlings.
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