Seroprevalence Of Anti Toxoplasma gondii IgG and IgM Among Pregnant Women in Sana’a Capital and Capital Trusteeship

(Ashraf Mohammed daytime and Abdel-Halim Salem Al-Tamimi)

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Abstract

From 463 pregnant women serum samples were collected through 2007 and 2008 for detection of specific anti-Toxoplasma gondii antibodies at Sana a capital and capital trusteeship. The serological test used for diagnosis is the enzyme linked immunosorbent assay (ELISA) method for anti Toxoplasma gondii IgG and IgM detection. When ELISA was applied on serum samples obtained from pregnant women were seen in, 194 samples (41.90 %) were seropositive for anti T. gondii IgG and 55 (11.88 %) for anti T. gondii IgM (Table 1). The highest percentage of IgG seropositivity obtained in the age groups of (> 40 years) where 2 (50.0%) of the samples examined were +ve for anti T. gondii IgG, followed by age group (31-40 years), 24 (45.3%), then age group (21-30 years), 110 (42.1%) and finally age group (&8804; 20 year), 58 (40.0%) (Table 2). On The other hand, IgM antibodies were highest percentage obtained in the age groups of (31-40 years) where 10 (18.9%) of the samples examined were +ve for anti T. gondii IgM, followed by age group (21-30 years), 29 (11.1 %) and age group (&8804; 20 year), 16 (11.0%) (Table 3). The present study confirmed the presence of Toxoplasmosis pregnant women at Sana a capital and capital trusteeship and the risk represented by this protozoan infection. It may be appropriate to screen women before and during pregnancy, any raise in seropositivity should be dealt with in order to minimise the consequences of this infection. Key Words: Toxoplasma gondii, Toxoplasma IgG and IgM, Pregnant women, ELISA, and Sana a Yemen.
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