Synthesis of New N-alkyl-O-acyl hydroxamic acid derivatives

(Yasser bin Suleiman al-Fayez)

---

Abstract

A wide array of useful N-alkyl-O-acyl- hydroxamic acid derivatives have been prepared. Both aromatic and aliphatic N-acyl side chains were tolerated in the preparation methods. The results have shown that the nature of N-acyl chains and N-alkyl group affects the yields of these products. It has been found that butyl and phenylacetyl groups in (1f) are the best R and R1 groups to use respectively, however the other R and R1 which were examined were also tolerated for successful preparation to be observed. The yield of these compounds are relatively low, this may be because of competitive formation of by products (1a-f).
PDF

References